Last year, at this time, there was a shortage in the availability of undecenoic acid. One company suggested that their customers switch to another product containing calcium undecylenate, a “salt” form of undecenoic acid. Other similar salt forms include potassium undecylenate, sodium undecylenate, and zinc undecylenate. This was an attempt to retain the sales that were being lost on a daily basis, but it was a very inferior choice to the undecenoic acid, as it always has been. Some people bought into this recommendation, which did very little to benefit them and only benefited the company.
Undecenoic acid is produced via a distillation process from castor bean oil. It is also known as 10-undecenoic acid or undecylenic acid. It was used effectively in World War II as a topical antifungal for foot fungus in soldiers wearing boots under demanding conditions. Due to its effectiveness against fungus, it was chosen as one of the first-line treatments against the occurrence of fungal candida overgrowth and related diseases that exploded onto the scene after the introduction of antibiotics in the 1940s. Dosages that were used in studies from 1949 and 1950 were 16 to 20 times those being used today. These studies showed safe and impressive results with only some gas and bloating noted in a few people at those high dosages. Current recommend dosages are much lower and less than one gram, .75mg per day. With the medical profession moving away from sound evidence-based treatments and towards pharmaceutical interventions, the use of undecenoic acid became less popular.
Antibiotic use and side effects continued to increase over the next few decades. Antifungal drugs were found to be toxic and less effective than hoped for. The use of antifungal drugs added a new dimension of difficulty by creating stronger antifungal resistant strains of candida that were harder to eradicate. Patients taking many of these drugs had to be monitored for liver and kidney damaged that was common with their use. Fungal candida quickly became the leading cause of hospital deaths due to fungus and the 4th overall leading cause of death in hospitals due to infections. A need for a safer and effective treatment approaches resulted in the re-introduction of undecenoic acid as a valid choice based on past successes. Initial successes appeared very quickly once again. With the use of an antifungal diet along with undecenoic acid, the dosage was dropped dramatically and treatment results were even more remarkable.
Initial concerns over the use of the acid form of undecenoic acid led to development of a buffered form where sodium, calcium, potassium, and zinc were combined with the undecenoic acid to form an undecylenate salt. The salt form of undecenoic acid, however, had very limited success due to its inability to function in anything other than a strong acid pH. This limited its usefulness to the stomach alone. Attempts to increase the acidity by adding HCL and time-released HCL to the formulations didn’t improve success rates. Although studies showed that the salt form could be as much as 30 times more effective than the original acid form, this effectiveness was never to be realized in the human body. This proved to be unnecessary as the original undecenoic acid form had huge clinical success.
Today, undecenoic acid is the leading choice among physicians as a choice in balancing candida in the body. How it achieves its success against candida is still not clearly known. Some scientists believe it is via its acid pH effect inside the cell, while others believe that it is undecenoic acid’s ability to alter the composition of fatty acids in the cell membrane leading to an inability to sustain its fungal form. The latter explanation appears to match clinical observations best. It’s 11-carbon atom structure has shown to be the most effective against fungal candida, and other fungi. It has been shown to be 6 times as effective as caprylic acid, the next best competitor available over the counter. There are some concerns with caprylic acid creating some stress to the kidneys, while undecenoic acid does not.
Undecenoic acid works in a safe, effective manner which does not harm the other microbes and cells of the body. By weakening the cell wall membrane of fungal candida it forces it to convert back to its normal yeast form. With the cell wall weakened, it becomes more vulnerable to the body’s own immune system defenses. By boosting the correct immune response, the body is then able to eliminate the excess yeast populations, leaving only healthy candida yeast cells present.
While the undecylenate salts may present as a better choice for stomach candida, they are very ineffective against candida anywhere else in the body. The superior and time-proven choice in addressing fungal candida continues to be undecenoic acid. Make undecenoic acid your choice in supporting healthy levels of candida in the body.
Get started today with Dr. McCombs Candida Plan.