There’s no problem with opening the Detox Essentials capsules and mixing them with water to swallow. We don’t recommend that for the Candida Force and Vital Flora products. Candida Force is very acidic and bitter and  Vital Flora is protected in a capsule to help the good bacteria survive the stomach acids. Vital Flora and Candida Force both come in small capsules. We have had some people who courageously opened the Candida Force capsules and swallow them, and then swallow water right away. We don’t encourage that, but they were able to do the Candida Plan that way.